Experimental Hemorrhage

Experimental Subarachnoid Hemorrhage

Background and Purpose Cerebral vasospasm after subarachnoid hemorrhage may result partially from the imbalance between vasodilator and vasoconstrictor factors. The vasodilator peptides substance P and calcitonin gene-related peptide contained in the trigeminovascular system are involved in the vasomotor phenomenon occurring after subarachnoid hemorrhage. The delayed arterial narrowing may refl...

[Somatosensory evoked potential in experimental intracerebral hemorrhage].

Cerebral Hemorrhage in Experimental Renal Hypertension.

Cerebral hemorrhages are one of the most important causes of death in hypertensive subjects in Japan. Throughout the world, however, there have been a few studies of the pathogenesis of cerebral hemorrhages. In this paper, cerebral hemorrhages were produced by experimental renal hypertension. The fibrinoid necrosis of the small arteries and arterioles in the brain seemed to be the primary patho...

Experimental Subarachnoid Hemorrhage in Spontaneously Hypertensive Rats

The influence of chronic arterial hypertension upon the permeability to albumin of the cerebral capillaries, i.e. the blood-brain barrier, was studied in normotensive Wistar and spontaneously hypertensive Wistar rats with experimental subarachnoid hemorrhage. The blood-brain barrier permeability to albumin was assessed quantitatively by spectrophotometric determination of Evans blue extravasati...

Enhanced pulmonary inflammation following experimental intracerebral hemorrhage.

The association between brain damage and respiratory dysfunction has been recognized although mechanistic link between the two is still poorly defined. Intracerebral hemorrhage is accompanied by brain injury, stroke, and parenchymal hematoma formation with surrounding inflammation. Increase intracranial pressure as a result of intracerebral hemorrhage may promote localized activation of cytokin...